The San Francisco 49ers got a taste of what their defense looks like without Nick Bosa in the second half of a loss to ...

After falling to 5-5 with a disappointing 20-17 loss to the Seattle Seahawks on Sunday, the San Francisco 49ers received even ...

One of the reasons the San Francisco 49ers get touted as an amazing offense is because of Deebo Samuel. Well, he's been anything but amazing this season. Samuel ...

In his third day of testimony Nima Momeni, who is on trial for the stabbing death of Cash App founder Bob Lee seemed to ...

Nima Momeni, the man accused of murdering Bob Lee, was peppered with dozens of questions from San Francisco jurors. Full ...

Dramatic video shows a man being rescued on Sunday after dangling from the edge of a cliff in San Francisco, California. The California Highway Patrol helicopter responded to the scene as the man ...

Quarterback Brock Purdy is day-to-day with a sore right shoulder, and EDGE Nick Bosa will be evaluated throughout the week ...

The San Francisco 49ers have injury issues at two of the most important positions on their roster entering Week 12. San Francisco 49ers head coach Kyle Shanahan spoke to reporters during a Monday ...

Matt Alexander appears poised to keep his job after eking out a victory over challenger John Jersin for the fourth and final ...

The Wu administration has wrapped up the third and final round of SPACE grants aimed at using $10 million in federal funds to support small businesses that are filling empty storefronts in downtown ...

American Christmas Tree Lighting’ on Friday, at 5 p.m. ET during a special edition of ‘The Five.’ Co-hosts Harold Ford Jr., Greg Gutfeld, Dana Perino, Judge Jeanine Pirro, Jessica Tarlov and Jesse ...

Sam Altman is on incoming San Francisco Mayor Daniel Lurie's transition team, along with other figures from law, government and philanthropy.